Cognitive Support Formula*

8 Probiotic Strains,
including our Proprietary 5-strain Blend

15 Billion Active Cultures plus B12, B6, B5
& folic acid

Probiotic Dietary Supplement 30 Vegetarian Capsules

Probiotic Dietary Supplement 30 Vegetarian Capsules

Product Details

Bio360® Cognitive Support Formula 

Did you know 95% of your brain’s serotonin receptors are in the gut?3 Some call the gut your second brain. Bio360® combines clinically proven^ probiotic cultures and nutrients designed to work along the gut-brain axis in one smart formula.*

Bio360® Cognitive Support Formula combines a proprietary five-strain blend backed by over 700 studies, with three additional, targeted probiotic strains and vitamins for stimulant-free mental energy, overall brain support and to help promote whole-body health.*

  • Proprietary 5-Strain Probiotic blend, which includes the #1 clinically studied probiotic strain (Lactobacillus rhamnosus GG strain) and the most independently studied probiotic strain (Lactobacillus plantarum WCFS1)
  • Vitamins B6 & B12 contribute to the normal function of the nervous system and support a feeling of less fatigue.*
  • Pantothenic acid (B5) contributes to the synthesis of some neurotransmitters.*
  • Folic acid plays a role in the nervous system as a neuroprotectant.*
non-GMO, no artificial flavors, no artificial colors
no preservatives, no added sugar, gluten free
dairy free, soy free, vegan

 Proud supporter of No Kid Hungry

3.Gershon MD, et al.. The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology. 2007;132(1):397-414.


There’s more to those “gut instincts” and “butterflies in your stomach”  than you think. Many people have called the gut a second brain, and for good reason. The digestive tract is surrounded by a web of endocrine cells that produce and store neurotransmitters, serotonin and dopamine. These cells “talk” to the brain and vice versa by way of the Vagus nerve.4

Your microbiome plays an important part in your mental health and well-being. 95% of your body’s serotonin is produced in the gut and sent to the brain. So when you’re stressed, anxious, or your diet is less than ideal, the good bacteria in your gut may be out of balance, and in turn may make you feel out of balance.

A key probiotic in the Bio360® Cognitive Support Formula includes Lactobacillus Rhamnosus, which has been shown to reduce stress-induced anxiety* by modulating GABA receptors and reducing the release of harmful hormones.5

Learn more about the science-driven ingredients inside Bio360® »

4. Carabotti M, et al. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015;28(2):203-209.

5. Bravo JA, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A. 2011;108(38):16050-16055.